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1.
Southeast Asian J Trop Med Public Health ; 2008 Jan; 39(1): 123-9
Article in English | IMSEAR | ID: sea-35657

ABSTRACT

This is the first reported case of bacillary angiomatosis associated with Bartonella henselae in Thailand. The clinical, pathological, and microbiological findings are presented. The bacterium was isolated from a biopsy of skin lesions obtained on admission and identified by cellular morphology, characteristics of colonies on chocolate agar, extensive biochemical tests and 16S ribosomal DNA sequencing.


Subject(s)
Adult , Angiomatosis, Bacillary/microbiology , Bartonella henselae/genetics , Base Sequence , Female , HIV Infections , Humans , Molecular Sequence Data , Skin/microbiology , Thailand
2.
Article in English | IMSEAR | ID: sea-44685

ABSTRACT

Brucellosis remains a major zoonotic disease worldwide. It has never been reported at King Chulalongkorn Memorial Hospital (KCMH). The authors describe the first case of brucellosis in KCMH, and also review all previous reports in Thailand. The presented case was a 52-year-old Thai man, living in Phetchabun Province, who was diagnosed with idiopathic pulmonary fibrosis two years prior to admission. He presented with prolonged fever, dry cough, weight loss of eight kg over three months, hepatosplenomegaly, and pancytopenia. Blood and bone marrow cultures grew Brucella melitensis at 72 hours of incubation. A slide agglutination (Rose Bengal) test was also positive for Brucella antibody. He had been exposed to contaminated placenta of his goats that had spontaneous abortion in the past few months before his illness. The patient was successfully treated with gentamicin, doxycycline, and rifampicin. Clinicians should have a high index of suspicion when evaluating patients presenting with prolonged fever and having an exposure risk of brucellosis.


Subject(s)
Animals , Anti-Bacterial Agents/therapeutic use , Brucella melitensis/isolation & purification , Brucellosis/diagnosis , Doxycycline/therapeutic use , Drug Therapy, Combination , Enzyme Inhibitors/therapeutic use , Fever , Fluorescent Dyes/diagnosis , Gentamicins/therapeutic use , Goats , Hospitals , Humans , Literature , Male , Middle Aged , Rifampin/therapeutic use , Rose Bengal/diagnosis , Thailand
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